Panama City 4-star Hotels

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Popular 4-star hotels in Panama City

These hotels are some of our user’s favourites in Panama City based on booking data. Prices were last updated on 30 April 2026.
Enter your travel dates to find the best prices.
Avenida Balboa, Panama City, Panama
Let yourself be carried away by an unparalleled experience at the facilities of the most incredible hotel in Latin America and discover a luxury service inspired to make you feel like a true star. Strategically located in a central point of the great city of Panama, with immediate access to Megapolis Outlets Mall, casino, and the Megapolis Convention Center. Just 20 minutes away from the Tocumen International Airport, 8 minutes from the Old Town and 5 minutes from the City's Financial District.Characterized by imposing architecture, stunning views, infinity pool, the best entertainment, and luxury restaurants framed in an exclusive gastronomic offer for your palate, Megapolis Hotel Panama is your ideal destination.
Free Wi-Fi
Parking
8.4
Excellent
3461 reviews
Location
1.1 km from city centre
Avenida Balboa-Multicentro, Panama City, Panama
Be part of the vibrant and cosmopolitan Panamanian culture at Hotel Decapolis, our hotel located in the heart of Panama City, by the seaside and just steps away from the coastal walkway.We offer first-class accommodation and services in our facilities that blend elegant and modern design with local art, creating a unique atmosphere in the city.We are connected to Megapolis Outlets Mall, where you'll find shops, restaurants, cinemas, the Majestic Casino, and the Megapolis Convention Center, where you can host any business event or enjoy shows. Each of the Hotel Decapolis rooms is well-equipped with amenities to ensure a comfortable stay. The rooms feature air conditioning, ensuring a pleasant environment regardless of the weather outside. Other room amenities include a flat-screen cable TV with Netflix, a spacious laptop-sized safe, a coffee maker, and a minibar, enhancing guest comfort and convenience. Guests can enjoy free Wi-Fi in their rooms, allowing them to stay connected during their visit. Furthermore, the rooms offer city or sea views, providing picturesque scenes for guests to admire.The hotel offers various amenities, including a heated outdoor pool and a gym, providing guests with opportunities to relax and exercise during their stay. Decapolis Hotel provides 24-hour reception service, concierge service, and room service. There are popular restaurants near the hotel, including Martini Sushi Bar, Petit Bistro, Fusion, and Hard Rock Caf, offering you plenty of options to enjoy Panamanian and international cuisine. For guests arriving by car, the hotel offers free private parking, which is a valuable benefit in a bustling city like Panama City.
Free Wi-Fi
Parking
8.1
Excellent
5496 reviews
Location
1.2 km from city centre
581 Calle Gaspar Hernandez Y Via Argent, Corregimiento El Cangrejo - Sector Bellavista, Panama City, PA, Panama City, Panama
Best Western Plus Panama Zen is strategically located in one of the best areas of Panama City, close to the financial and business district, shopping malls, restaurants, bars and casinos, and is only 16 kilometers from Tocumen International Airport. It is your ideal accommodation for wonderful days in Panama City, whether on a business or leisure trip. Enjoy our pool with a view of the city, restaurant, gym, business center, meeting rooms and more. The rooms have air conditioning, minibar (with additional charge), safe, 39-inch LCD TV with cable channels, hair dryer, coffee maker, cordless telephone, wake-up call service, clock radio and desk. Free high-speed Wi-Fi Internet access and parking. In our restaurant you can try the best of Panamanian cuisine, with delicious dishes and flavors. It will be a pleasure to welcome you to Best Western Plus Panama Zen!
Free Wi-Fi
8.6
Excellent
4561 reviews
Location
0.6 km from city centre
Plaza de la Independencia, C. 5a Este, Panama City, Panama
Located in the heart of the Casco Viejo, Central Hotel Panama is an icon of elegance, heritage, and hospitality. Originally opened in 1874 and fully restored, it is the first hotel in the city and a historic landmark that forms part of the UNESCO World Heritage Site. With 135 thoughtfully designed rooms offering comfort and sophistication, the hotel blends the classic charm of its historical legacy with all the modern amenities. Each space provides a unique experience that connects the past with the present, in one of Panamas most vibrant cultural districts.
Free Wi-Fi
8.4
Excellent
2324 reviews
Location
3.7 km from city centre
€155
Via Israel y Calle 71, San Francisco, Panama City, Panama
Welcome to the Ramada Plaza Panama Punta Pacifica, a refreshing getaway spot less than 20 kilometers from Tocumen International Airport! This full-service lodging in Panama is close to the exclusive Multiplaza mall, historic Old Panama, and the ATLAPA Convention Center. Onsite, partake in full leisure amenities and services such as - spa with facial and massage services, panoramic fitness center, outdoor pool, bar and restaurant. Take advantage of complimentary Valet Parking, as well as a business center and meeting rooms. Enjoy complimentary breakfast daily, and complimentary High Speed Internet access in rooms and public spaces. Our comfortable guest rooms feature, a business desk, safebox, mini fridge, coffeemaker, iPod docking station and HDTV. Book an affordable hotel room online today. Service animals are welcome at this hotel. All property is smoke free.
Free Wi-Fi
Parking
9.2
Excellent
3693 reviews
Location
2.0 km from city centre
8001 Amador Ave. & Pelicano Ave. Panama City, Panama, Panama City, Panama
Along with 2 restaurants, this smoke-free hotel has 2 outdoor pools and a fitness center. Free WiFi in public areas, free self parking, and a free shopping center shuttle are also provided. Additionally, a bar/lounge, a snack bar/deli, and a 24-hour business center are onsite. Radisson Hotel Panama Canal offers 254 accommodations with minibars and laptop-compatible safes. Pillowtop beds feature premium bedding. LCD televisions come with premium cable channels. Microwaves and coffee/tea makers are provided. Bathrooms include shower/tub combinations, complimentary toiletries, and hair dryers. This Panama City hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and phones. Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is provided daily. 2 outdoor swimming pools are on site along with a children's pool. Other recreational amenities include a fitness center. The recreational activities listed below are available either on site or nearby; fees may apply.
Free Wi-Fi
Parking
8.1
Excellent
3278 reviews
Location
5.8 km from city centre
56 y 57 East Street, Obarrio, Panama City, Panama
A vibrant and energetic environment in downtown Panama City, Panama for Panamanians and global travelers who crave the exceptional in every corner of life. At Sortis Hotel, Spa & Casino you are in charge and you decide your own rhythm. Your own heartbeat. Here, everything has been crafted with the guest experience in mind — from 391 high-design rooms, suites and apartments to a striking, ultramodern style that infuses every moment of the guest experience. Restaurants include Manabí, a rustic, contemporary restaurant showcasing modern Panamanian cuisine. Score, a globally inspired Sports Bar and Lounge. The pool scene, overlooking stunning city and skyline views, goes seamlessly from day to night. In addition to a family friendly kids pool and arcade, it also includes Acua, a poolside Bar and Lounge.
Free Wi-Fi
8.2
Excellent
801 reviews
Location
0.7 km from city centre
€109
Calle Ramon H Jurado Edifico P, Panama City, Panama
Residence Inn Panama City is an extended-stay hotel that helps you feel connected while away from home, with spacious rooms featuring fully equipped kitchens. Our Panama City, Panama hotel is located in an exclusive area inside the Pacific Center complex, which includes a mall, hospital, theater, and cinema. If you're looking for a hotel near Pacific Center Mall, we're just steps from Multiplaza Mall and walking distance to Balboa Avenue and Cinta Costera. With easy access to South Corridor, Costa del Este is a short drive away. We're also close to the Panama Canal, Smithsonian Marine Exhibition Center, and Biomuseo. Whether you're relocating or vacationing, our hotel in downtown Panama City, Panama offer homelike surroundings, pet-friendly lodging, and thoughtful amenities to help you balance life and work.
Free Wi-Fi
Parking
9.0
Excellent
285 reviews
Location
1.7 km from city centre
€131
Multiplaza Pacific Mall, Via Israel Avenue, Panama City, Panama
Enjoy your stay, your way at Courtyard Panama Multiplaza Mall. Located near Punta Pacifica inside the Multiplaza Panama. Our Multiplaza Panama hotel, offers incomparable access not only to the mall's wealth of retail outlets and restaurants but to many other popular Panama City destinations, such as the Atlapa Convention Center. After your long day, relax and unwind at our pet-friendly hotel in Panama City, Panama rooms and suites, outfitted with complimentary Wi-Fi, mini-refrigerators, flat-panel TVs and room service. Please your palate with a delectable dish from our restaurant, or order your drink from our bar. Host your upcoming business meeting or wedding reception in one of our four event rooms featuring catering services, AV equipment and in-house decorators. Additionally, our business center provides computers, as well as copying and printing services, to help you prepare for your presentation. Whatever brings you to our hotel Panama City, Panama, Courtyard as all you need for a relaxing stay.
Free Wi-Fi
Parking
8.5
Excellent
988 reviews
Location
1.4 km from city centre
Avenida Domingo Diaz via Tocumen, Centro Comercial MetroMall, Panama City, Panama
Transform your stay into a relaxing getaway at Courtyard Panama Metromall, one of the top hotels near Tocumen Airport. Our hotel next to Metromall on Avenida Domingo Díaz Panama is close to Tocumen International Airport and Hipódromo Presidente Remon. Enjoy free parking and easy access to nearby attractions. After a busy day, unwind in soundproof rooms with free Wi-Fi, mini-refrigerators, and room service. Savor breakfast or dinner at Centro, our on-site restaurant and bar. Stay active in our fitness center or outdoor pool. Whether you're here for leisure or business, our hotel is ideal for travelers seeking San Miguelito business hotels in Panama, with two stylish event spaces perfect for meetings or receptions
Free Wi-Fi
Parking
8.6
Excellent
800 reviews
Location
11.3 km from city centre

Travel insights for hotels in Panama City

Use these up-to-date, data-driven insights about booking a hotel in Panama City including ideal times to book, pricing trends, and more.

What is the cheapest month to book a hotel in Panama City?

The cheapest month to book a hotel in Panama City is August (€133). Conversely, the most expensive month to stay in Panama City is January (€239).

What is the cheapest day to stay in a hotel in Panama City?

The cheapest day to stay in Panama City is Wednesday (€145). On the other hand, travelers can expect to pay the most on Thursday, when the average nightly price is €165.

How much is a hotel in Panama City tonight?

Users have found prices for hotels in Panama City tonight starting as low as €16, rising to an average cost of €132, based on searches in the last 72 hours. Prices start from €40 for a 4-star hotel in Panama City for tonight.

How much is a Panama City hotel room this weekend?

In the past 72 hours, we’ve seen prices for hotels in Panama City this weekend for as little as €20/night. If you’re specifically looking for a 3-star hotel this weekend, our users have found prices as low as €20/night. For a 4-star hotel in Panama City, the cheapest rate recently found was €45/night for this weekend.

How far ahead should you book a hotel in Panama City?

Save money by booking a hotel at least 85 days before your trip to Panama City. The lowest price found when booking 85 days ahead was €13 per night.

Top-rated 4-star Panama City hotels

View deals on 4-star hotels in Panama City that have the highest user reviews. Review data was last updated on 30 April 2026.
These are some of the highest-rated 4-star hotels in Panama City based on user reviews.
Omar Torrijos Avenue, Panama City, Panama
14.1 km from city centre
Free Wi-Fi
Parking
€159
Avg. per night
Via Israel And 77th Street, Panama City, Panama
2.7 km from city centre
Free Wi-Fi
€106
Avg. per night

Cheapest 4-star hotels in Panama City

Discover affordable 4-star hotels in Panama City that provide a quality experience without breaking the bank. 4-star hotels in Panama City can be found for as little as €39 per night. Price data was last updated on 30 April 2026
These are the lowest-priced 4-star hotels our users have recently found in Panama City. Prices may vary based on dates selected and hotel location.
Calle 53 Marbella y Avenida 5a B Sur, Panama City, Panama
0.8 km from city centre
Free Wi-Fi
Parking
€39
Avg. per night
Calle D Zona 9, Panama City, Panama
0.3 km from city centre
Free Wi-Fi
Parking
€46
Avg. per night
Calle 33 Este A 100 Mts de Ave. Balboa, Panama City, Panama
2.1 km from city centre
Free Wi-Fi
Parking
€46
Avg. per night
El Cangrejo, Via Argentina, Calle Jose Fabregas Frente al Power Club y Diagonal al Restaurante 7 Mares, Panama City, Panama
0.4 km from city centre
Free Wi-Fi
Parking
€48
Avg. per night
Calle Miguel Brostella, Panama City, Panama
2.9 km from city centre
Free Wi-Fi
Parking
€50
Avg. per night
Avenida Eloy Alfaro y Calle 11, Panama City, Panama
3.5 km from city centre
Free Wi-Fi
€55
Avg. per night
Calle Jose I. Fabrega y Thais de Pons Panama City 581 PA, Panama City, Panama
0.8 km from city centre
Free Wi-Fi
Parking
€58
Avg. per night
Avenida 2da Sur, Obarrio, Bella Vista, Panama City, Panama
0.1 km from city centre
Free Wi-Fi
€64
Avg. per night
Calle Ricardo Arango Y Calle 53e, Panama City, Panama
0.4 km from city centre
Free Wi-Fi
Parking
€69
Avg. per night
El Cangrejo, Calle D, Bella Vista, Panama City, Panama
0.2 km from city centre
Free Wi-Fi
Parking
€74
Avg. per night
Calle 52, Panama City, Panama
0.3 km from city centre
Free Wi-Fi
Parking
€74
Avg. per night
Vía Tocumen Tocumen 0819-09190 PA, Panama City, Panama
16.5 km from city centre
Free Wi-Fi
Parking
€75
Avg. per night

Other star-rated hotels in Panama City

Hotels that are booked the most in each class receive the “Most popular” badge. Hotels with the “Best value” have the most attractive prices based on their popularity. Price data was last updated on 30 April 2026.
Not set on a 4-star hotel? We’ve got plenty of other options for you to choose from. These are the most popular and best value properties in Panama City based on hotel class.
5 stars
Calle Punta Colon, Punta Pacifica, Panama City, Panama
€226
083500257 Avenida Aquilino de la Guardia (C/ Aquilino de la Guardia) Panama City, Panama, Panama City, Panama
€147
Calle 50, Urb. Marbella, Panama City, Panama
€126
3 stars
Italy Avenue, Punta Paitilla, Panama City, Panama
Via Argentina Calle Principal, 49, Panama City, Panama
Calle Eusebio A. Morales Lote # C-5, Panama City, Panama
Via Argentina y Jose Marti, 17, Panama City, Panama
Calle 49 Bella Vista, Panama City, Panama
2 stars and under

Other accommodations in Panama City

Find deals on places to stay in Panama City that are not hotels. These are just a few of the most popular hostels and vacation rentals in the area. Pricing information was last updated on 30 April 2026.
Looking for something less traditional for your stay? Find the perfect hostel or vacation rental for your trip in Panama City.
Calle 54 Este Casa 7, Panama City, Panama
0.8 km from city centre
Free Wi-Fi
Airport shuttle
€32
Avg. per night
Esquina de Ave B y Calle 12, Panama City, Panama
3.6 km from city centre
Free Wi-Fi
€36
Avg. per night
Calle Enrique Malek, Panama City, Panama
17.9 km from city centre
Free Wi-Fi
Parking
€38
Avg. per night
Calle Ramon H Jurado Edifico P, Panama City, Panama
1.7 km from city centre
Free Wi-Fi
Parking
€131
Avg. per night
Calle Eusebio A. Morales y Calle 55, Panama City, Panama
0.4 km from city centre
Free Wi-Fi
Parking
€81
Avg. per night
Miramar Plaza, Balboa Avenue, P.O. Box 7336, Panama City, Panama
1.0 km from city centre
Free Wi-Fi
€176
Avg. per night

Where to stay in Panama City

Explore different areas within Panama City to find the perfect location for your stay. Map data was last updated on 30 April 2026.
The map below shows all 4-star hotels in Panama City. Zoom in to find popular attractions and click on a nearby hotel for more information about the property.

Facts about 4-star hotels in Panama City

Find useful tips and insights about 4-star hotels in Panama City to help you make the most of your experience. FAQs were last updated on 30 April 2026.
  • What is the cheapest 4-star hotel in Panama City?

    In Panama City, you can stay at Hotel Roma Plaza, the most affordable 4-star hotel, priced from €23 per night.

  • What is the best 4-star hotel in Panama City?

    In Panama City, the best 4-star hotel is Hotel La Compañía Casco Antiguo, renowned for its 9.3 user rating and an average price of €397 per night.

Stay elsewhere in Panama City