Popular hotels
Cheapest hotels
Where to stay

Hotels near Mayo Clinic, Rochester

Search and compare hotels near Mayo Clinic from hundreds of travel sites on HotelsCombined and save.

Mayo Clinic - Rochester, MN, United States
1 May — 2 May2
...and more

Learn why travellers love HotelsCombined

Compare hotel ratings collected from thousands of user reviews.

One search gives you accurate pricing on affordable hotels.

Customie your results by hotel chain, amenities, price and more.

Search for hotels as many times as you want – for free.

Refine Your Search

Star ratings
Guest Ratings
Amenities
Freebies
See all filters

Popular hotels near Mayo Clinic

Discover well-known properties in Mayo Clinic that are favoured by visitors more than others. There are 102 hotels in Mayo Clinic and price data was last updated on 24 April 2025. The average price for a hotel in Mayo Clinic is .
The following hotels are among the most sought after in the Mayo Clinic area. If you're not finding the hotel you're looking for and have flexibility with dates, try adjusting the search form at the top of the page for more options.
Filter by star ratings
All filters
9 3rd Avenue Northwest, Rochester, MN, United States
Hotel with free breakfast, a quick walk to Mayo Clinic Along with an indoor pool, this smoke-free hotel has a restaurant and a fitness center. Free self-serve breakfast and free WiFi in public areas are also provided. Other amenities include a bar/lounge, a coffee shop/cafe, and self parking. Housekeeping is available on request. Kahler Inn and Suites - Mayo Clinic Area offers 271 air-conditioned accommodations with coffee/tea makers and irons/ironing boards. Flat-screen televisions come with cable channels and pay movies. Rooms have partially open bathrooms. Bathrooms include showers and complimentary toiletries. Guests can surf the web using the complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Housekeeping is provided on request. Recreational amenities at the hotel include an indoor pool and a fitness center. The recreational activities listed below are available either on site or nearby; fees may apply.
Pool
Free Wi-Fi
6.9
Good
2010 reviews
Location
1.6 km from city centre
€134
20 2nd Avenue Southwest, Rochester, MN, United States
Central Rochester hotel connected to the convention center, steps from Mayo Clinic 2 restaurants, an indoor pool, and a 24-hour fitness center are available at this smoke-free hotel. WiFi in public areas is free. Additionally, a bar/lounge, a sauna, and a conference center are onsite. Housekeeping is available once per stay. Kahler Grand Hotel offers 552 air-conditioned accommodations with coffee/tea makers and hair dryers. Beds feature premium bedding. Televisions come with cable channels and pay movies. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include bathtubs or showers and complimentary toiletries. Guests can surf the web using the complimentary wireless Internet access. Business-friendly amenities include desks and desk chairs, as well as phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is offered once per stay and change of bedsheets can be requested. Housekeeping is provided on a limited basis. An indoor pool and a hot tub are on site. Other recreational amenities include a sauna and a 24-hour fitness center. Children under 17 years old are not allowed in the swimming pool, fitness facility, or hot tub without adult supervision. The recreational activities listed below are available either on site or nearby; fees may apply.
Pool
Free Wi-Fi
7.1
Good
1827 reviews
Location
1.5 km from city centre
€149
225 South Broadway, Rochester, MN, United States
The Hilton Garden Inn Rochester Downtown hotel of Minnesota is in the heart of downtown connected via skywalk to the Mayo Clinic, University of Minnesota Rochester, Shops of University Square mall, the Mayo Civic Center, and the Government Center as well as many restaurants and theaters. At Hilton Garden Inn Rochester hotel of Minnesota, we have complimentary shuttle service available to the Mayo Clinic and hospitals. Deluxe accommodations, friendly Minnesota service and a relaxed atmosphere await our guests. At Hilton Garden Inn Rochester hotel of Minnesota, we are certain to please the busy executive or leisure traveler in the downtown Rochester area of Minnesota with our array of special amenities, including complimentary high-speed Internet access with secure PrinterOn remote printing, in-room hospitality center with a microwave, refrigerator, coffee maker, two dual line phones with voicemail and data ports, large work desk with desk level outlets, ergonomic chair, On Command video, TV video games, complimentary HBO, complimentary USA Today each weekday morning, heated indoor pool, whirlpool, fitness center and 24-hour complimentary business center. The Hilton Garden Inn Rochester hotel of Minnesota offers 850 square feet of meeting space that accommodates up to 70 people. The Great American Grill restaurant serves freshly prepared breakfasts. The Pavilion Pantry has a selection of refrigerated, frozen and microwaveable packaged items perfect for in-room preparation. A number of restaurants are within walking distance of our downtown Rochester, Minnesota hotel. When Hilton Garden Inn Rochester Downtown hotel guests are ready for after work relaxation or some fun during a weekend getaway in downtown Rochester, Minnesota, the indoor hotel pool and fitness center are available. Walking and bicycling paths are just 2 blocks away and Silver Lake Park is just one mile from Hilton Garden Inn Rochester hotel of Minnesota. ***** Everything. Right where you need it. *****
Pool
Free Wi-Fi
8.3
Excellent
372 reviews
Location
1.4 km from city centre
€120
401 6th Street Southwest, Rochester, MN, United States
Family-friendly Rochester hotel in Historic Southwest with free breakfast An indoor pool, a restaurant, and a 24-hour fitness center are available at this hotel. Free buffet breakfast is provided, as well as free WiFi in public areas, free self parking, and a free area shuttle. Additionally, a bar/lounge, a 24-hour business center, and a spa tub are onsite. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area offers 214 air-conditioned accommodations with safes and coffee/tea makers. 42-inch flat-screen televisions come with cable channels. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include shower/tub combinations, complimentary toiletries, and hair dryers. Guests can surf the web using the complimentary wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Housekeeping is provided daily. An indoor pool, a children's pool, and a spa tub are on site. Other recreational amenities include a 24-hour fitness center. Children under 17 years old are not allowed in the swimming pool or spa tub without adult supervision. The recreational activities listed below are available either on site or nearby; fees may apply.
Pool
Free Wi-Fi
Parking
8.0
Excellent
608 reviews
Location
0.8 km from city centre
€125
10 East Center Street, Rochester, MN, United States
The Hilton Rochester Mayo Clinic Area is conveniently located in the heart of downtown Rochester, just two short blocks from the world-famous Mayo Clinic. The hotel is 8 miles from Rochester International Airport, with service to Chicago O’Hare and Atlanta. Interstate 90, the main thoroughfare from Madison, Wisconsin: Chicago, Illinois: and points east is also 8 miles from downtown. I-35 North is 40 minutes away, providing access from Des Moines, Iowa: St. Louis, Missouri: and Kansas City. The Minneapolis St Paul International Airport is 80 miles away, and there are up to 50 shuttles a day which fly between the city and that airport. We are renowned for personalized friendly guest service. Our tastefully decorated hotel features contemporary elegance, designed to ensure every need of the medical patient, corporate, conference and any other traveler. Spacious guest rooms of various sizes and a variety of suites offer a long list of guest amenities with generous work surfaces, comfortable seating, luxurious Hilton bedding, and free high-speed internet access in addition to other services. WiFi is available in public areas throughout the hotel. A comfortable and spacious Tech Lounge is located in the Main Lobby for guest use. Our guests enjoy the following services and amenities: -A chauffeur-driven limousine with on-demand transfer to and from Mayo Clinic facilities and various locations within the city. -A Steak House Signature Restaurant, open for Lunch and Dinner -A casual Restaurant open for Breakfast, Lunch and Dinner -A Herb ‘n Kitchen outlet -Room Service -Concierge Services -Valet Parking -Indoor Swimming Pool, Whirlpool, Saunas and Sundeck. -A Spacious Precor Exercise Facility. -An attractive outdoor Terrace designed for relaxation and exercise on the roof of the fourth floor of the hotel. The Hilton Rochester Mayo Clinic Area Conference Center has 24,000 square feet of flexible meeting and banquet room including two magnificent ballrooms with 19-foot ceilings, three breakout rooms, and ample pre-function space. The Conference Center has state-of-the-art audio visual equipment. Our friendly catering services staff attends to every detail for the most successful event. Whether it is for a conference, banquet, seminar, wedding or reception, our facilities with panoramic views over the city provide the perfect location. This downtown Hilton hotel, just one block from the Mayo Civic Center, is connected to the city skyway system, providing a climate-controlled environment for guests to access the Mayo Clinic, University Square Shopping Mall, downtown restaurants, Mayo Civic Center, University of Minnesota Rochester campus, the Courthouse and many other locations. The Mayo Clinic Art Tour, Mayowood, home of Dr. Charles Mayo: Rochester Art Center, and Rochester Civic Theater are among the various locations of interest within the city. Amish Country, the Mississippi Valley and Lanesboro, a quaint Arts village, are all within a 40-minute drive of the hotel. The Mall of America is 80 miles away and adjacent to the Minneapolis St. Paul Airport. Transportation is available. Hilton Rochester Mayo Clinic Area is the perfect location to stay and enjoy a relaxing respite in contemporary elegance, with first-class personalized, friendly service.
Pool
8.8
Excellent
171 reviews
Location
1.6 km from city centre
€176
441 West Center St. Nw, Rochester, MN, United States
The Residence Inn Rochester Mayo Clinic Area is conveniently located downtown Rochester, MN within walking distance to the world-famous Mayo Clinic. Enjoy a well-appointed 1 or 2 bedroom suite with a sofa bed, kitchen with microwave, full-size fridge, stovetop, dishwasher, and cookware. Complimentary amenities include a hot breakfast each morning, Wi-Fi access, a 24-hour fitness center, and a rooftop patio. Host up to 20 people for a business meeting in the Silver Lake Meeting room. The Residence Inn Rochester Mayo Clinic Area is 9 miles from the Rochester International Airport and provides access to Mayo Clinic via a indoor pedestrian walkway. Our hotel in downtown Rochester, MN is centrally located to St. Mary’s Hospital and Methodist Hospital. Please be aware our hotel will be undergoing a full renovation beginning in November of 2024 until April of 2025. We look forward to providing our guests with an extraordinary transformation to improve your experience with updated guest rooms, lobby and amenities.
Free Wi-Fi
8.2
Excellent
92 reviews
Location
1.5 km from city centre
€161
1211 2nd Street, Rochester, MN, United States
Hotel with free breakfast, steps from Mayo Clinic Hospital - Saint Marys Campus This smoke-free hotel features an indoor pool, a fitness center, and a 24-hour business center. Free full breakfast is provided, as well as free WiFi in public areas, free self parking, and a free area shuttle. Other amenities include a spa tub, coffee/tea in a common area, and a business center. Housekeeping is not available. Aspen Suites offers 82 air-conditioned accommodations with DVD players and safes. Accommodations offer separate sitting areas. Beds feature premium bedding. 32-inch flat-screen televisions come with premium cable channels. Accommodations at this 3-star hotel have kitchenettes with stovetops, microwaves, cookware/dishes/utensils, and dishwashers. Guests can surf the web using the complimentary wired and wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include coffee/tea makers and irons/ironing boards. Housekeeping is offered daily and hair dryers can be requested. An indoor pool and a spa tub are on site. Other recreational amenities include a fitness center.
Pool
Free Wi-Fi
8.6
Excellent
162 reviews
Location
1.6 km from city centre
€143
101 1st Avenue Southwest, Rochester, MN, United States
Directly connected to the Mayo Clinic, Rochester Marriott Mayo Clinic Area, hotel offers easy access to some of the city's most popular attractions via underground climate-controlled pedestrian walkways and skyways. Shop at University Square and enjoy biking, running and several trails nearby. Or visit Minneapolis and Saint Paul, an easy day trip from Rochester, MN. Host an event or board meeting in our hotel's modern venues or unwind after a busy day at our in house restaurant Salute. Business travelers, enjoy spacious guest rooms with work areas and complimentary Wi-Fi. All our rooms and suites feature luxurious bedding and HDTVs, plus a wealth of upscale amenities. Find modern luxury downtown Rochester at Rochester Marriott Mayo Clinic Area.Please be aware our hotel will be undergoing a full renovation beginning in November of 2024 until April of 2025. We look forward to providing our guests with an extraordinary transformation to improve your experience with updated guest rooms, lobby and restaurant.
Pool
Free Wi-Fi
8.0
Excellent
285 reviews
Location
1.4 km from city centre
€201
123 Fourth Ave. NW, Rochester, MN, United States
Hotel with free breakfast, a quick walk to Mayo Clinic A 24-hour business center, self parking, and laundry facilities are available at this smoke-free hotel. Free continental breakfast and free WiFi in public areas are also provided. Other amenities include a 24-hour front desk and free newspapers. Brentwood Inn & Suites offers 93 accommodations with complimentary newspapers and coffee/tea makers. Refrigerators and microwaves are provided. Guests can surf the web using the complimentary wireless Internet access. Flat-screen televisions come with premium cable channels. Irons/ironing boards and hair dryers can be requested. Housekeeping is provided daily.
Free Wi-Fi
7.9
Good
33 reviews
Location
1.7 km from city centre
€116
20 2nd Avenue Southwest, Rochester, MN, United States
Central hotel with 2 restaurants connected to a shopping center in Rochester This smoke-free hotel features 2 restaurants, an indoor pool, and a fitness center. Free self-serve breakfast is provided, as well as free WiFi in public areas, free valet parking, and a free manager's reception. Other amenities include a bar/lounge, a coffee shop/cafe, and coffee/tea in a common area. The Towers At Kahler Grand Hotel offers 44 accommodations with complimentary bottled water and coffee/tea makers. Each accommodation is individually furnished and decorated. Beds feature down comforters and premium bedding. Plasma televisions come with digital channels and pay movies. Bathrooms include showers, bathrobes, designer toiletries, and complimentary toiletries. Guests can surf the web using the complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Additionally, rooms include hair dryers and irons/ironing boards. A nightly turndown service is provided and housekeeping is offered daily. Recreational amenities at the hotel include an indoor pool and a fitness center.
Pool
Free Wi-Fi
7.7
Good
22 reviews
Location
1.5 km from city centre
€172

Cheapest hotels near Mayo Clinic, Rochester

Discover affordable stays in Mayo Clinic that provide a quality experience without breaking the bank. Hotels in Mayo Clinic can be found for as low as €51 per night. There is currently one property in Mayo Clinic that can be booked for this price. Baymont by Wyndham Rochester Mayo Clinic Area is one of the hotels that can be booked for the lowest price in Mayo Clinic. Price data was last updated on 24 April 2025
For those on a budget, these are the cheapest hotels available close to Mayo Clinic for the selected dates. If you have flexibility with arrival and departure, use the search form to compare prices for other dates.
Show all 102 hotels
1230 South Broadway, Rochester, MN, United States
0.9 km from city centre
Pool
Free Wi-Fi
Parking
€51
Avg. per night
1215 2nd Street Southwest, Rochester, MN, United States
1.6 km from city centre
Free Wi-Fi
Parking
€81
Avg. per night
435 16th Avenue Northwest, Rochester, MN, United States
2.3 km from city centre
Pool
Free Wi-Fi
Parking
€81
Avg. per night
161 13th Avenue Southwest, Rochester, MN, United States
1.7 km from city centre
Pool
Free Wi-Fi
€102
Avg. per night
470 17th Avenue Northwest, Rochester, MN, United States
2.4 km from city centre
Pool
Free Wi-Fi
Parking
€104
Avg. per night
1125 2nd Street Southwest, Rochester, MN, United States
1.5 km from city centre
Pool
Free Wi-Fi
Parking
€105
Avg. per night
155 16th Avenue Southwest, Rochester, MN, United States
1.8 km from city centre
Pool
Free Wi-Fi
Parking
€107
Avg. per night
165 13th Avenue Southwest, Rochester, MN, United States
1.7 km from city centre
Pool
Free Wi-Fi
€111
Avg. per night

Other accommodations in Mayo Clinic

Find the perfect hostel, theme hotel, or holiday rental for your stay in Mayo Clinic.
Show all 102 stays
441 West Center St. Nw, Rochester, MN, United States
1.5 km from city centre
Free Wi-Fi
€161
Avg. per night
161 13th Avenue Southwest, Rochester, MN, United States
1.7 km from city centre
Pool
Free Wi-Fi
€102
Avg. per night
225 South Broadway, Rochester, MN, United States
1.4 km from city centre
Pool
Free Wi-Fi
€120
Avg. per night

Where to stay in Mayo Clinic

Explore different neighbourhoods and areas within Mayo Clinic to find the perfect location for your stay. Map data was last updated on 24 April 2025.
Scroll to and zoom in on the areas close to Mayo Clinic you plan on visiting to find nearby properties. Clicking a property's name will unlock more information and allow you to book that particular hotel.

Facts about staying in Mayo Clinic

Find useful tips and insights about staying in Mayo Clinic to help you make the most of your experience. FAQs were last updated on 24 April 2025.
  • What are the best hotels near Mayo Clinic?

    Kahler Grand Hotel (7.1/10 from 1,827 reviews), Hilton Garden Inn Rochester Downtown (8.3/10 from 372 reviews), and SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys (8.4/10 from 366 reviews) are all highly-rated places to stay near Mayo Clinic.

  • What is a good hotel near Galway City Center?

    Reviews of The G Hotel and Spa recommend it as a good place to stay near Galway City Center, scoring 8.7/10 from 1,734 ratings.

  • What is a good hotel in Mayo Clinic near Dublin City Centre?

    Hotel Riu Plaza The Gresham Dublin is the most recommended hotel near Dublin City Centre on HotelsCombined (scoring 8.7 over 7,129 reviews).

  • Is there a good hotel near Old Town Of Albufeira?

    1,122 HotelsCombined reviews of Eden Villas & Apartments score it 8.8/10, making it a highly recommended hotel near Old Town Of Albufeira.

  • How much is a cheap hotel near Mayo Clinic?

    €48 per night is the cheapest Mayo Clinic hotel price found in our data from the last 72 hours.

  • What are the most popular landmarks to visit in Mayo Clinic?

    The most popular landmark in Mayo Clinic is Galway City Center located in Galway, followed by Dublin City Centre and Old Town Of Albufeira, located in Dublin and Albufeira, respectively. Depending on where and how long you plan on staying in Mayo Clinic, you may be able to visit at least one of these cities.

See more FAQs

Find better results for your stay in Mayo Clinic